welche blutwerte bei erschöpfung — can a microbiome test help?

When evaluating exhaustion, standard blood tests are more evidence-based than microbiome analysis. Key markers include: iron/ferritin (iron deficiency), vitamin B12, folate, vitamin D, thyroid function (TSH, fT3, fT4), cortisol (diurnal profile), inflammatory markers (CRP), and complete blood count. A microbiome test may offer indirect clues if gut-brain axis disruption or low-grade inflammation is suspected, e.g., in irritable bowel syndrome or non-specific digestive issues. However, the evidence linking specific gut bacteria to fatigue is still preliminary (mostly association studies). Microbiome testing should not replace a medical workup of the above blood values. Caveat: home tests lack clinical validation for diagnosing fatigue; results can be misleading without professional interpretation. In summary: start with blood work, consider microbiome only as an adjunct if gut symptoms are present.