wann ist der crp wert erhöht — can a DNA test help?

CRP (C-reactive protein) is a non-specific marker of inflammation. It is elevated in acute infections (bacterial, viral), tissue damage (trauma, surgery), chronic inflammatory diseases (rheumatoid arthritis, vasculitis), autoimmune conditions, obesity, smoking, and metabolic syndrome. Mild elevations (2–10 mg/L) also occur in subclinical inflammation. A DNA test cannot diagnose the cause of elevated CRP. While genetic variants (e.g., in the CRP gene) influence baseline CRP levels, they are not clinically actionable. Evidence from bidirectional Mendelian randomization shows CRP is a risk marker, not a causal factor for cardiovascular disease (PMID 37298077). Therefore, genetic testing for CRP polymorphisms is not recommended for individual health management. If CRP is elevated, medical evaluation is necessary – the test for inflammatory markers (e.g., hsCRP) is a blood test, not a DNA test. Commercial DNA tests for CRP provide no clinically useful information.