Myths vs facts: Östradiol and Abnehmen

Estradiol plays a complex role in fat metabolism. It promotes fat oxidation and inhibits fat storage, especially in subcutaneous depots. Low estradiol levels (e.g., during menopause) are associated with increased visceral fat and weight gain. However, effects are dose-dependent and individual. Hormone replacement therapy may help some women with weight management, but it is not a weight-loss drug. Evidence comes from observational and clinical studies, not from RCTs with weight loss as primary endpoint. Many myths exaggerate the effects. Fact: Estradiol influences metabolism, but weight loss still requires calorie deficit and exercise. Caution: Hormone therapy should only be used under medical indication, not for weight reduction.