Folic acid (vitamin B9) is essential for skin health due to its role in DNA synthesis, repair, and cell division. Adequate intake supports skin regeneration, may help prevent premature aging, and promotes wound healing. Studies suggest that folate deficiency is linked to increased photosensitivity and pigmentation disorders. However, evidence from randomized controlled trials is limited; much of the knowledge comes from observational or mechanistic studies. Consumer DNA tests analyzing folate-related genes (e.g., MTHFR) only indicate metabolic capacity, not actual folate levels in blood or skin. Supplementation should not be undertaken without medical advice, as high-dose folic acid can mask vitamin B12 deficiency. Overall, folic acid plays a supportive but not standalone role in skin health – a balanced diet rich in leafy greens usually provides sufficient folate.
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