Triglyceride senken: which supplements make sense?

To lower elevated triglycerides, several supplements are discussed, but evidence varies. Omega-3 fatty acids (EPA/DHA) at 2–4 g/day have the strongest support, reducing triglycerides by 20–30% in human trials. Niacin (vitamin B3) is effective but limited by side effects like flushing and hepatotoxicity. Berberine shows moderate effects in meta-analyses, similar to statins, but may cause GI issues. Red yeast rice contains monacolin K (a natural statin) and can lower triglycerides, but quality and safety concerns exist. Other supplements like garlic, curcumin, or green tea extract have weaker or inconsistent evidence. Crucially, supplements should not replace dietary changes (reducing sugar, increasing fiber) and exercise. For severely elevated triglycerides (>500 mg/dL), medical evaluation and prescription options (fibrates, high-dose omega-3) are necessary. Evidence rating: human-moderate for omega-3; mixed/mechanistic for others. Caution: potential interactions with blood thinners.