The direct relationship between glucose and menopause is not addressed in the provided context. However, established medical knowledge indicates that declining estrogen levels during menopause can reduce insulin sensitivity, leading to higher fasting glucose and increased risk of type 2 diabetes. Many women experience worsening glucose tolerance during perimenopause. Underlying mechanisms include changes in fat distribution (increased visceral fat) and reduced glucose uptake in muscle. Lifestyle factors such as diet and exercise are critical. Genetic testing for single variants (e.g., TCF7L2) has limited predictive value. The evidence for this link is moderate, based on epidemiological and physiological studies, not on the sources given here. Individualized medical or nutritional counseling is recommended.
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