wie lange gluten essen vor zöliakie-test — which blood markers matter?

The question about how long to eat gluten before a celiac test is clinically important, but the provided context does not address it. Based on established guidelines (e.g., ESPGHAN, ACG), patients should consume a gluten-containing diet for at least 4–6 weeks before serological testing. Typical intake is 1–2 servings of gluten per day (about 2 g gluten, equivalent to one slice of bread). Key blood markers: IgA-tissue transglutaminase antibodies (tTG-IgA) as first-line screening, and IgA-endomysial antibodies (EMA) for confirmation. If IgA deficiency is present, IgG-based tests (e.g., IgG-deamidated gliadin peptides) are used. Genetic testing for HLA-DQ2/DQ8 can assess risk but does not replace biopsy in uncertain cases. Crucially, a gluten-free diet before testing can lead to false negatives. Evidence is strong (human-strong) from clinical studies and guidelines. Sources: PMID 25680370, PMID 27021120.