What role does Ferritin Eisenmangel play in Allergie?

Ferritin is a marker of iron stores; low ferritin indicates iron deficiency. Iron deficiency can affect immune function, particularly T‑cell activity and antibody production. Some studies suggest a link between iron deficiency and increased allergy risk or exacerbated allergic responses, because iron is essential for immune cell maturation and function. However, the evidence is mixed: some research shows an association between low ferritin and higher allergy prevalence, while other studies find no effect or even a protective role of iron deficiency. Additionally, symptoms of iron deficiency (fatigue, poor concentration) can overlap with allergy symptoms. Therefore, a single ferritin measurement is insufficient to diagnose or explain allergies. Clinical relevance remains uncertain. If iron deficiency or allergy is suspected, a physician should perform a comprehensive workup including complete blood count, IgE, and specific allergy tests. The evidence is based on mechanistic and observational studies, not large randomized controlled trials.