welche blutwerte bei erschöpfung und müdigkeit — can a DNA test help?

For exhaustion and fatigue, common blood tests include iron/ferritin, vitamin B12, vitamin D, thyroid markers (TSH, fT3, fT4), cortisol, complete blood count (hemoglobin), inflammatory markers (CRP), and fasting glucose. A DNA test can provide additional clues but does not replace blood work. The provided context includes genes such as CYP2C19 (affects drug metabolism, e.g., antidepressants), GSTM1 (detoxification), LCT/MCM6 (lactose digestion), and PCSK9 (cholesterol). These may be indirectly linked to fatigue – for example through intolerances or metabolic issues – but the evidence is mostly mechanistic or observational. No direct causal relationship between these variants and general fatigue is established. Therefore, the utility of DNA tests for fatigue is limited; they may at best prompt more targeted blood tests. Importantly, many individuals with 'risk variants' remain healthy. Medical evaluation of the mentioned blood values remains the priority.