Zöliakie Glutenunverträglichkeit-Test: can a microbiome test help?

A microbiome test can reveal gut dysbiosis often associated with celiac disease, but it is not a diagnostic tool. Celiac diagnosis requires serology (tTG-IgA) and duodenal biopsy. Research indicates that individuals with celiac disease frequently have reduced microbial diversity and increased Proteobacteria. A microbiome test might theoretically help monitor adherence to a gluten-free diet or identify other food sensitivities. However, evidence is limited: no specific microbial signature reliably confirms or excludes celiac disease. Many commercial tests overstate their utility. Therefore, while a microbiome test can provide supportive information, it should not replace standard medical evaluation. If celiac disease is suspected, consult a gastroenterologist.