Whether lowering cortisol directly promotes longevity is not yet conclusively proven. Cortisol, the primary stress hormone, becomes chronically elevated under persistent stress. Long-term high cortisol is linked to adverse health outcomes: hypertension, insulin resistance, visceral obesity, immune suppression, and accelerated cellular aging (telomere shortening). These mechanisms could theoretically shorten lifespan, so reducing cortisol – via stress management, sleep optimization, exercise, or adaptogens – seems a plausible strategy to extend healthspan. However, robust human trials demonstrating a causal link between cortisol reduction and increased life expectancy are lacking. Current evidence is mostly mechanistic and epidemiological, with some animal studies. Furthermore, excessive cortisol suppression can be dangerous (adrenal insufficiency). Therefore, any intervention should be medically supervised. In summary: biologically plausible, but clinical evidence for longevity is weak.
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