was ist cortisol einfach erklärt — can a DNA test help?

Cortisol is a vital hormone produced by the adrenal glands, often called the 'stress hormone'. It regulates energy metabolism, blood sugar, immune function, and the sleep-wake cycle. A healthy cortisol level follows a natural rhythm: high in the morning, low at night. Chronic stress can disrupt this rhythm, leading to elevated or depleted levels, which may contribute to fatigue, weight gain, and sleep issues. A DNA test can identify genetic variants (e.g., in COMT or FKBP5) that influence how your body handles stress and cortisol regulation. However, these tests are not diagnostic and cannot measure your actual cortisol levels. The evidence is mixed: some associations are supported by research, but the predictive power for an individual is limited. If you suspect a cortisol imbalance (e.g., Cushing's or adrenal insufficiency), consult a doctor for proper lab testing.