Magnesium is often marketed as a skin cure-all – from acne to anti-aging. The scientific evidence is limited. Magnesium is indeed a cofactor for over 300 enzymes, including those involved in skin barrier function and inflammation regulation. Deficiency may contribute to dry, irritated skin, but a direct causal link to specific skin conditions like acne or eczema is not well established. Studies show that topical magnesium (e.g., magnesium chloride spray) can help inflammatory skin conditions like atopic dermatitis by strengthening the barrier and reducing itch. Oral supplementation, however, has only weak effects on skin unless a true deficiency exists. Many claims rely on animal or in vitro data that do not translate directly to humans. High doses can cause diarrhea and electrolyte imbalances. Bottom line: magnesium is relevant for skin health but not a miracle cure. A balanced diet and targeted testing for deficiency are more sensible than blind supplementation.
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