How are FUT2 and Sport related?

The relationship between FUT2 (fucosyltransferase 2) and sport is not well established. FUT2 determines secretor status, which influences gut microbiome composition and vitamin B12 absorption. Some studies suggest a link between FUT2 variants and gut microbiota, which could indirectly affect nutrient availability and inflammation – both relevant for athletic performance and recovery. However, direct, reproducible studies showing a clear effect of FUT2 on endurance, strength, or recovery are lacking. The evidence is therefore mechanistic or unclear. Consumer DNA tests that analyze FUT2 can report secretor status, but deriving sports optimization from this is speculative. No clinical guidelines recommend FUT2 testing for athletes. Be cautious of exaggerated marketing claims. Anyone considering dietary or supplementation adjustments (e.g., B12) should consult a healthcare professional.