What role does Vitamin D 25-OH play in Wechseljahre?

Vitamin D (25-OH) is the circulating storage form and plays a key role in calcium metabolism and bone health. During menopause, declining estrogen accelerates bone loss, increasing osteoporosis risk. Adequate vitamin D levels are therefore essential to maintain bone density. Additionally, some evidence suggests vitamin D may influence mood, immune function, and possibly hot flashes, but the evidence is moderate and not conclusive. MyBody-X tests can analyze genetic variants in the VDR gene that affect vitamin D metabolism, but they do not replace medical diagnosis. Serum levels should be measured before supplementation. Overdosing must be avoided. The evidence for bone health is strong, while for other menopausal effects it is moderate.