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Is Folsäure useful for menopause?

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Is Folsäure useful for menopause?

Whether folic acid is useful during menopause cannot be answered with a simple yes. Folic acid (vitamin B9) is crucial for DNA synthesis and homocysteine metabolism. During menopause, homocysteine levels often rise, potentially increasing cardiovascular risk. Studies indicate that adequate folate intake can lower homocysteine, but direct benefits for menopausal symptoms like hot flashes or bone density loss are not clearly proven. Moreover, the body must convert synthetic folic acid into its active form (methylfolate). Women with MTHFR variants (e.g., A1298C) have reduced conversion capacity, making methylfolate potentially more effective. However, the evidence is moderate, not strong. High-dose folic acid can mask vitamin B12 deficiency, a concern for older women. A balanced diet rich in natural folate (leafy greens, legumes) is usually sufficient. Before supplementing, check homocysteine and B12 levels. Marketing claims that folic acid is an 'anti-aging miracle' are not supported by robust science.

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