Whether TSH (thyroid-stimulating hormone) is useful for longevity requires a nuanced answer. TSH is a well-established clinical marker for thyroid function. Hypothyroidism and hyperthyroidism can affect metabolism, cardiovascular health, and overall well-being—all factors linked to lifespan. However, a single TSH measurement is not a direct longevity test. Evidence comes from epidemiological studies showing that both subclinical and overt thyroid disorders are associated with increased mortality. Thus, TSH is useful for detecting and managing thyroid dysfunction, which can impact longevity. The provided context does not contain specific information on TSH and longevity, so the evidence grade is human-observational. Caveat: A normal TSH does not guarantee longevity; it is just one piece of a broader health assessment.
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