Myths vs facts: HbA1c and Fruchtbarkeit

HbA1c reflects average blood glucose over 2–3 months and is primarily used for diabetes management. Myth: A normal HbA1c guarantees good fertility. Fact: HbA1c is a risk marker, not a direct fertility test. In women trying to conceive, elevated HbA1c is associated with ovulatory dysfunction, increased miscarriage risk, and pregnancy complications. In men, elevated HbA1c may impair sperm quality (motility, DNA integrity). However, evidence is mostly observational with moderate effect sizes. A normal HbA1c does not rule out other fertility issues. Relying solely on HbA1c for fertility assessment is insufficient; it should be interpreted alongside hormone profiles, lifestyle, and clinical evaluation. Beware of marketing claims that overstate a causal link. Evidence level: human-moderate, based on observational studies and clinical practice.