Evidence check: CRP Entzündung in the context of Allergie

CRP (C-reactive protein) is a non-specific inflammatory marker that rises in many acute and chronic inflammatory conditions, including allergies. However, the elevation in allergic reactions is usually mild and not diagnostically decisive. Studies show that in allergic rhinitis or asthma, high-sensitivity CRP (hs-CRP) may be slightly elevated, but the correlation with disease activity is weak. More specific markers like IgE, eosinophils, or skin tests are far more informative for allergy diagnosis. A blood CRP test (not DNA) can serve as a rough indicator of systemic inflammation but does not replace allergological workup. Consumer DNA tests analyzing CRP gene variants (e.g., rs1205, rs1800947) have small effect sizes and are not clinically actionable. Evidence is based on GWAS and observational studies, not RCTs. In summary, CRP in the allergy context is a non-specific, supplementary marker. If allergy is suspected, established diagnostic methods should be used. MyBody-X tests do not provide direct allergy diagnosis.