Question
What is the approximate increased risk of late-onset Alzheimer's disease for individuals carrying one APOE4 allele compared to those with the ε3/ε3 genotype?
Health · EN
What is the approximate increased risk of late-onset Alzheimer's disease for individuals carrying one APOE4 allele compared to those with the ε3/ε3 genotype?
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TIKKI knowledge answer
Carrying one copy (ε3/ε4) raises risk approximately 2- to 3-fold compared to the ε3/ε3 genotype.
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