How are ADH1B and Schlaf related?

For an athlete experiencing bloating, a DNA test cannot reliably determine gluten sensitivity. While tests for HLA-DQ variants (e.g., DQ2/DQ8) can indicate genetic risk for celiac disease – an autoimmune condition triggered by gluten – they do not diagnose non-celiac gluten sensitivity (NCGS). Bloating in athletes is often multifactorial: high fiber intake, FODMAPs, lactose, sorbitol, or exercise-induced changes in gut motility. A single genetic marker cannot distinguish these causes. The evidence for using DNA tests to guide gluten avoidance is weak (rated 'unclear'), and consumer tests often overstate single-gene effects. Clinical evaluation – including symptom diaries, elimination diets, and possibly IgE testing – remains the gold standard. Starting a gluten-free diet without a confirmed diagnosis may lead to unnecessary restrictions and potential nutrient deficiencies, especially for athletes with high energy demands.