How are CRP Entzündung and Schlaf related?

C-reactive protein (CRP) is a systemic inflammation marker. Epidemiological studies consistently show that short sleep duration (<6 h), poor sleep quality, and insomnia are associated with elevated CRP levels. The relationship appears bidirectional: inflammation can disrupt sleep, and sleep deprivation triggers inflammatory pathways (e.g., via NF‑κB). However, effect sizes are modest, and confounding factors (obesity, stress, comorbidities) are strong. Interventional trials show that improving sleep can lower CRP, but not all individuals respond equally. CRP is not a diagnostic test for sleep disorders; it is a non‑specific risk marker. For consumers, a single elevated CRP should not be interpreted as proof of poor sleep without clinical context. Evidence is based on observational and mechanistic studies; large RCTs are lacking. Therefore, while the link is plausible and supported by moderate evidence, clinical recommendations remain cautious.