Myths vs facts: Cardio Risk Check and Darmgesundheit

Myths vs. Facts: Cardio Risk Check and Gut Health **Cardio Risk Check:** Myth: A single DNA test can reliably predict your heart attack risk. Fact: Polygenic risk scores (PRS) for type 2 diabetes or cardiovascular disease are based on many small-effect SNPs (e.g., rs7903146, OR ~1.54). Their predictive power is limited, especially outside the ancestry used to develop them. Lifestyle factors (diet, exercise, smoking) have a far greater impact. Evidence is human-observational/GWAS, not clinically diagnostic. Caveat: MyBody-X markets such tests without published efficacy evidence (evidence grade: marketing). **Gut Health:** Myth: A DNA test can provide personalized dietary recommendations for a healthy gut. Fact: Gut health is shaped by the microbiome, diet, medications, and environment – not by single genes. Tests for food intolerances or 'gut bacteria' often lack validation and regulatory clearance (evidence grade: marketing). Safety note: Self-implemented elimination diets can lead to nutrient deficiencies. Consult a doctor or dietitian for genuine concerns.