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Evidence check: IgG in the context of Darmgesundheit

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Evidence check: IgG in the context of Darmgesundheit

IgG antibody testing for food sensitivities is often marketed in the context of gut health, but the scientific evidence is weak. IgG is a normal immunoglobulin produced after exposure to food proteins; its presence indicates exposure, not necessarily intolerance or pathology. Systematic reviews and position statements (e.g., from the European Academy of Allergy and Clinical Immunology) conclude that IgG-based food sensitivity tests lack clinical validity and are not recommended for diagnosing food intolerance or gut disorders. Elevated IgG levels are common in healthy individuals and do not correlate with symptoms. The gold standard for identifying food intolerances remains a symptom diary, elimination diet, and, where indicated, validated tests such as lactose hydrogen breath testing or duodenal biopsy for celiac disease. Marketing IgG panels as a 'gut health check' is misleading. Caveat: Do not initiate restrictive diets based solely on IgG results without professional guidance.

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