FADS1 encodes a key enzyme in the desaturation of omega-3 and omega-6 fatty acids. Genetic variants can alter enzyme efficiency, potentially affecting the balance of pro- and anti-inflammatory lipid mediators, which in turn may influence skin barrier function, acne, eczema, and overall skin health. However, the evidence is largely mechanistic or based on GWAS associations; direct, actionable skin-care recommendations from a single FADS1 SNP are not well-supported. MyBody-X tests provide a genetic insight, not a clinical diagnosis. Diet and lifestyle—especially adequate intake of EPA/DHA from fish or algae and limiting omega-6 excess—are more impactful. For persistent skin issues, consult a dermatologist. Safety note: Do not self-prescribe high-dose supplements based on genetic data alone.
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