Myths vs facts: CYP1A2 and Haut

CYP1A2 is a liver enzyme primarily responsible for metabolizing caffeine and certain drugs. Regarding skin health, many claims circulate that lack solid evidence. **Fact:** CYP1A2 determines how fast you break down caffeine. Caffeine has antioxidant and anti-inflammatory properties that could theoretically affect skin – for example, sun protection or acne. **Myth:** A direct, clinically meaningful link between a specific CYP1A2 variant and skin conditions (e.g., wrinkling, eczema) is not well established. Most data come from animal or in-vitro studies. The evidence is weak to conflicting. Knowing your CYP1A2 status should not drive skincare decisions. A genetic test alone cannot replace a dermatological evaluation.