Common mistakes around Helicobacter pylori in children involve both diagnosis and treatment. A positive stool antigen test does not automatically indicate an active infection—it may reflect past infection or a false positive. Many parents and even clinicians start treatment without confirmation via endoscopy with biopsy or a urea breath test. This is problematic because unnecessary antibiotic use promotes resistance. Another mistake is assuming that every childhood abdominal pain is caused by H. pylori. In reality, most pediatric abdominal pain is functional and not infection-related. Even when infection is confirmed, the indication for treatment in children remains controversial, as the benefit is not clearly established. Furthermore, eradication therapy must be completed fully—stopping early fosters resistance. Resistance testing before treatment is often overlooked. Finally, the possibility of reinfection or persistence after therapy is not always monitored. Parents should always seek medical evaluation and not rely solely on self-tests or online information. The evidence base is moderate to strong for diagnostic methods and treatment, but clinical decisions must be individualized.
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