Evidence check: Cortisol senken in the context of fertility

The question of lowering cortisol in the context of fertility is scientifically relevant, but the evidence is moderate. Chronically elevated cortisol can suppress gonadotropin release (LH, FSH) via the HPA axis, potentially disrupting ovulation or impairing sperm quality. However, most data come from observational studies or animal models; randomized controlled trials proving a causal effect of cortisol reduction on fertility are largely lacking. Lifestyle interventions such as stress reduction, sleep optimization, and moderate exercise can lower cortisol, but individual responses vary. DTC tests claiming a 'cortisol score' from genetic markers are not evidence-based – cortisol is primarily influenced by environment and circadian rhythm, not single SNPs. For fertility, clinical parameters (cycle, hormone status, semen analysis) are key. Salivary or serum cortisol measurement can be useful but only as part of a medical workup. Caution against self-medication or 'cortisol diets'. Conclusion: lowering cortisol may be supportive but does not replace fertility diagnostics.