How are Zink and longevity related?

Zinc is an essential trace mineral critical for immune function, antioxidant defense (e.g., superoxide dismutase), DNA repair, and regulation of cellular senescence. Aging is associated with declining zinc status, which may contribute to chronic inflammation and oxidative damage. Observational studies link low serum zinc to higher all-cause mortality in older adults. However, randomized controlled trials have not consistently shown that zinc supplementation extends lifespan in healthy individuals. The evidence is moderate, relying on mechanistic plausibility and epidemiological associations rather than robust clinical trials. High doses can be toxic and interfere with copper absorption. Therefore, supplementation should be based on confirmed deficiency, not generic longevity claims. Direct-to-consumer tests often overstate zinc's role in extending lifespan.