What role does Zöliakie Test play in Wechseljahre?

The celiac test (typically HLA-DQ2/DQ8 genotyping) plays a limited but potentially relevant role in menopause. Celiac disease can cause symptoms like fatigue, osteoporosis, anemia, and mood changes – all of which overlap with menopausal complaints. A positive genetic test only indicates a predisposition (about 30 % of the population carry risk alleles), not active disease. Evidence for routine use in menopause is weak: no large studies show that genetic testing improves diagnosis or management in this life stage. Clinically, if celiac is suspected, serology (tTG-IgA) and duodenal biopsy are the gold standard. The genetic test can help rule out celiac if risk alleles are absent. Caveat: menopause itself can alter gut symptoms, so medical guidance is essential. Evidence: mechanistic/unclear.