Myths vs facts: CYP2D6 and Langlebigkeit

CYP2D6 is a drug-metabolizing enzyme, not directly linked to longevity. Myths claim that 'fast' or 'slow' metabolizers live longer – no robust evidence supports this. Variants affect how drugs (e.g., antidepressants, beta-blockers) are processed, which may indirectly influence health, but not lifespan per se. GWAS studies show no significant effects on longevity. Clinical relevance is limited to pharmacogenetics. Beware of exaggerated claims from direct-to-consumer tests: CYP2D6 status is not a 'longevity gene'. Evidence: mechanistic/unclear. Sources: none specific in context.