What to watch with CRP Entzündung and weight loss?

CRP (C-reactive protein) is a non-specific inflammation marker that rises with tissue damage, infection, or chronic inflammation. Weight loss – especially through calorie restriction and exercise – often reduces CRP because adipose tissue secretes pro-inflammatory cytokines. However, the relationship is not straightforward: rapid or extreme dieting can transiently increase CRP due to metabolic stress. Other factors like poor sleep, smoking, or occult infections also affect levels. Therefore, CRP should not be interpreted in isolation but alongside other markers (e.g., IL-6, TNF-α) and clinical context. For sustainable reduction, aim for gradual weight loss (0.5–1 kg/week), an anti-inflammatory diet (omega-3s, fiber), and regular physical activity. Caveat: a normal CRP does not rule out low-grade inflammation; an elevated level without symptoms warrants medical evaluation. Evidence is based on observational and interventional studies, but not from the provided context.