Longevity DNA Test: can a DNA test help?

A longevity DNA test can identify certain genetic variants associated with increased lifespan in observational studies, such as FOXO3 rs2802292. However, effect sizes are small, and results are not deterministic. Most longevity GWAS yield polygenic risk scores with limited predictive power. Consumer tests often overstate clinical relevance. Lifestyle factors (diet, exercise, sleep, stress management) have a far greater impact on healthy lifespan. A DNA test may serve as a motivational tool but does not replace evidence-based prevention. Be cautious of marketing claims that promise personalized 'longevity diets' based solely on genetics. Evidence is moderate (human-observational/GWAS).