Sport gene tests often claim to predict endurance, power, or injury risk based on single DNA variants like SIRT1 or ACTN3. However, the scientific evidence is generally weak: effect sizes are small, findings come from observational studies, and they do not reliably translate to athletic performance. A test may indicate a slight tendency but cannot determine whether someone will be a better endurance athlete. Marketing often overstates these links. Lifestyle factors like training, nutrition, and recovery are far more important. Gut microbiome tests can show inflammation markers (e.g., IL1B) and diet-related diversity, but clinical validity for performance optimization is limited. A sport gene test should be seen as an informative extra, not a decision-making tool. Be cautious of overblown claims: no test replaces personalized coaching or medical advice.
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