Myths vs facts: Pharmakogenetik Medicheck and Haut

The combination of pharmacogenetics and skin care (often marketed as 'Medicheck Haut') is frequently promoted as personalized medicine, but the scientific evidence is weak. While genetic variants can influence drug metabolism (e.g., CYP450 enzymes), there are few robust studies for skin conditions like acne, rosacea, or psoriasis that demonstrate clear clinical benefit. Most recommendations are based on theoretical mechanisms or small association studies. Direct impact on choosing creams or oral medications is not evidence-based. Moreover, many providers overstate the clinical relevance of single nucleotide polymorphisms (SNPs). A dermatologist remains essential for diagnosis and treatment. These tests may serve as supplementary information but cannot replace medical advice. Be cautious of exaggerated claims: the evidence is predominantly mechanistic or marketing-driven.