What role does AMH play in menopause?

AMH (Anti-Müllerian Hormone) is produced by granulosa cells of ovarian follicles and is the most reliable biomarker for ovarian reserve. AMH levels decline steadily with age and become undetectable after menopause. Clinically, AMH is used to predict the timing of menopause – low levels in women over 40 suggest approaching menopause. However, individual prediction is imprecise due to variable decline rates. AMH is also used in fertility medicine to assess response to stimulation. Important: An AMH test alone does not replace a full clinical evaluation. Direct-to-consumer tests measuring AMH often lack proper interpretation and may lead to false reassurance or unnecessary worry. The evidence linking AMH to menopause is strong (large human studies), but predictive accuracy is limited. Caveat: AMH does not reflect egg quality or overall health.