Myths vs facts: Ferritin and fertility

Ferritin is a storage protein for iron and is commonly used as a marker of body iron reserves. A common myth is that a normal ferritin level automatically indicates good fertility. In reality, the relationship is more nuanced: both low and high ferritin can impair fertility. Iron deficiency (low ferritin) can lead to anovulation, poor egg quality, and menstrual cycle disturbances. Conversely, iron overload (high ferritin) can increase oxidative stress and damage ovarian or testicular function. A single ferritin reading from a consumer test is not diagnostic for fertility issues. It must be interpreted alongside other iron parameters (transferrin saturation, hemoglobin) and clinical context. Evidence is based on observational studies; randomized controlled trials specifically linking ferritin to fertility outcomes are limited. Caution: iron supplements should only be taken if deficiency is confirmed, as excess iron is harmful. For a comprehensive fertility assessment, clinical hormone and functional testing is required.