How are Pharmakogenetik Medicheck and Allergie related?

The Pharmakogenetik Medicheck from MyBody-X analyzes genetic variants related to the metabolism of up to 900 drugs. Its focus is on intolerances (e.g., slow metabolism) rather than true allergies. Allergies are immune-mediated (e.g., HLA associations like HLA-B*5701 for abacavir), while the test primarily provides pharmacokinetic and pharmacodynamic hints. The clinical evidence for many of these markers is weak and often based on association studies. The manufacturer explicitly states that the test does not provide medical advice and should not be used to change medication independently. A direct link between the test and allergies exists only for a few well-established gene–drug pairs; for most allergies (e.g., penicillin), the test is not validated. Thus, the relationship is indirect and should be seen as supplementary information, not allergy diagnostics.