What to watch with FUT2 and Darmgesundheit?

FUT2 (fucosyltransferase 2) determines your secretor status and has well-documented links to gut health. Non-secretors (about 20 % of the population) lack the ability to express certain blood group antigens in bodily secretions, which alters the gut microbiome composition – typically lower diversity and a shift toward pro-inflammatory species. Non-secretor status is associated with a moderately increased risk of recurrent urinary tract infections, Crohn’s disease, and lower vitamin B12 levels. While a DNA test can identify your FUT2 genotype, the predictive power is modest: the associations are statistically robust but not deterministic. Gut health is primarily shaped by diet, fiber intake, probiotics, and lifestyle. A FUT2 result should be interpreted as a risk factor, not a diagnosis. If you are a non-secretor, consider monitoring B12 levels and discussing gut health with a healthcare provider. Evidence: human-moderate (GWAS, cohort studies).