What role does FUT2 play in Abnehmen?

FUT2 (fucosyltransferase 2) determines secretor status and influences gut microbiome composition and vitamin B12 absorption. Some GWAS have linked FUT2 variants (e.g., rs601338) to BMI, but effect sizes are very small (~0.1 kg/m² per allele) and not clinically actionable for weight loss. The evidence is primarily mechanistic (microbiome modulation) and based on population-level associations. No direct dietary or weight-loss recommendations can be derived from FUT2 status alone. Lifestyle factors (caloric balance, physical activity) remain far more important. Consumer DNA tests that include FUT2 should not be used as a standalone guide for weight management.