CRP (C-reactive protein) is a well-established inflammation marker produced in the liver. Elevated CRP (≥2–3 mg/L) is associated with increased risk of insulin resistance and type 2 diabetes – that is a fact, supported by epidemiological studies (e.g., PMID: 19381015). The myth is that CRP directly causes high blood sugar. In reality, chronic low-grade inflammation (often driven by visceral fat) promotes insulin resistance, which indirectly raises blood glucose. A single CRP value is not a diabetes test; it only indicates systemic inflammation. Lifestyle factors such as diet, exercise, and sleep influence both markers. For consumer lab tests: an elevated CRP alone does not diagnose diabetes but can serve as a risk indicator. Evidence is moderate to strong, but not causal at the single-biomarker level. Caveat: many confounders (smoking, obesity, infections) affect CRP. Fasting measurement and repeat testing are advisable.
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