Insulin and sport are closely linked, especially in blood glucose regulation. During exercise, insulin levels typically drop to allow glucose release from the liver. For individuals with insulin resistance or diabetes, physical activity can improve insulin sensitivity. Key considerations include carbohydrate timing: pre-workout slow carbs can sustain energy, while post-workout carbs plus protein replenish glycogen. Risk of hypoglycemia exists during prolonged or high-intensity exercise, particularly if using insulin or sulfonylureas. Evidence for genotype-based adjustments (e.g., FTO variants) is weak; general sports nutrition principles matter more. Caveat: Continuous glucose monitoring and medical supervision are recommended for those on glucose-lowering medications.
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