Evidence check: Progesteron in the context of Fruchtbarkeit

Progesterone is a key hormone in the female menstrual cycle and essential for fertility. It prepares the uterine lining for implantation of a fertilized egg and supports early pregnancy. Deficiency can cause cycle irregularities, recurrent miscarriage, or failure to conceive. Measuring progesterone levels (e.g., on cycle day 21) is a standard part of fertility assessment. However, a single measurement is often insufficient because progesterone is secreted in a pulsatile manner and varies greatly across the cycle. At-home tests (saliva or blood spot kits) may provide a rough indication but cannot replace clinical evaluation. Evidence for self-optimization with supplements (e.g., chasteberry) is limited and based on small studies. For unexplained infertility, consultation with a gynecologist or endocrinologist is strongly recommended.