Lay opinion often overestimates the power of DNA tests for children. Many believe a simple cheek swab can reveal the perfect diet or exercise plan. The evidence tells a more nuanced story: Lactose intolerance genetics (LCT/MCM6) is highly reliable (human-strong) and can help if a child has recurrent stomach issues after milk. Gluten sensitivity genetics (HLA-DQ2/DQ8) is useful to rule out celiac disease but not diagnostic (human-moderate). Claims about a 'perfect diet' or 'longevity polygenic score' for children are marketing hype. A replication study in Sardinian Blue Zones found no association for common longevity SNPs (PMC11680967). For children, clinical symptoms and breath tests are often more definitive than DNA tests. Parents should view these tests as limited tools, not crystal balls. The evidence is mixed: strong for lactose, moderate for celiac, weak for broad diet optimization.
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