hsCRP (high-sensitivity C-reactive protein) is a general marker of inflammation that can be elevated in many conditions, including infections, autoimmune diseases, and sometimes in allergic reactions. However, it is not specific for allergies. In allergic conditions like allergic rhinitis or asthma, hsCRP may be mildly elevated, but diagnosis and monitoring of allergies rely primarily on specific IgE antibodies, skin prick tests, and clinical symptoms. An elevated hsCRP alone does not confirm an allergy and can be influenced by other factors such as obesity, smoking, or minor infections. Therefore, hsCRP is not useful as a standalone test for allergies. It may have a role in assessing overall inflammatory status, but the evidence for its utility in allergy is moderate. For allergy evaluation, consult an allergist.
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