Myths vs facts: Lowering triglycerides during menopause. Fact: Estrogen decline in menopause can raise triglycerides because estrogen modulates lipoprotein lipase. Lowering is possible via lifestyle: Mediterranean diet, omega-3 fatty acids (fish, flaxseed), exercise, and weight management. Myth: Hormone replacement therapy always lowers triglycerides – oral estrogens may actually increase them; transdermal forms are more favorable. Myth: Supplements alone suffice – studies show omega-3 (2–4 g/day) and phytosterols have modest effects but require dietary changes. Caveat: Genetics (e.g., TCF7L2 variants) influence triglyceride metabolism, but lifestyle dominates. A single lab test (e.g., MyBody-X) can indicate trends but does not replace clinical diagnosis. Evidence: strong for general triglyceride lowering, moderate for menopause-specific data. Sources: no specific PMIDs in context; based on guidelines (AHA, ESC).
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