What should I know about unvertraglichkeit kaffee?

Coffee intolerance can stem from caffeine sensitivity (genetic variants in CYP1A2), stomach irritation from acids, or rare true allergy. IgG-based food intolerance tests for coffee lack scientific validation – they often yield false positives and are not recommended by allergy guidelines. A genetic test for caffeine metabolism (e.g., CYP1A2) may indicate slow or fast metabolism, but clinical utility is moderate. For persistent symptoms (palpitations, GI discomfort, anxiety), consult a doctor to rule out other conditions. Evidence: human-moderate (genetics), marketing/unclear (IgG). Sources: none specific in context; general guidelines.