What to watch with HbA1c and Fruchtbarkeit?

HbA1c (glycated hemoglobin) is a long-term blood glucose marker reflecting average levels over 2–3 months. Elevated HbA1c (≥5.7% or ≥39 mmol/mol) indicates impaired glucose tolerance or diabetes, which can affect fertility. In women with PCOS or unexplained infertility, higher HbA1c is linked to insulin resistance, ovulatory dysfunction, and poorer IVF outcomes. In men, elevated HbA1c may negatively impact sperm quality (motility, DNA fragmentation). However, HbA1c is not a direct fertility test—it serves as a risk marker. A normal HbA1c does not rule out fertility issues, as many other factors (hormones, anatomy, lifestyle) are involved. Evidence comes from observational studies and clinical practice, not from randomized controlled trials with fertility as primary endpoint. Caveat: HbA1c can be skewed by anemia, hemoglobin variants, or kidney disease. For those trying to conceive, an optimal HbA1c (<5.7%) is advisable, but comprehensive fertility workup is essential. MyBody-X does not offer a specific HbA1c test; this is a clinical lab test.