Myths vs facts: Selen and skin aging

Selenium is an essential trace mineral that acts as a cofactor for selenoproteins like glutathione peroxidases, which can reduce oxidative damage in skin cells. Myths often claim that high selenium doses cure acne or stop skin aging. In fact, studies show that selenium deficiency may accelerate skin aging, but supplementation beyond requirements provides no additional benefit and can be toxic in excess (selenosis). Evidence for anti-aging effects on skin is mostly mechanistic and observational; robust randomized controlled trials are lacking. MyBody-X tests can measure selenium status in blood and analyze genetic variants (e.g., in GPX1) that affect selenium utilization. The app uses this data for personalized advice, but effects are small. Maintaining adequate selenium is important, but it is not a miracle anti-aging supplement. Caveat: Supplementation only advisable if deficiency is confirmed.