What role does Hormoncheck Frauen play in allergy?

The Hormoncheck Frauen (measuring estradiol, progesterone, testosterone, cortisol, etc.) is designed to assess female hormonal status – for cycle irregularities, menopause, or fertility. Its role in allergy is indirect and not evidence-based as a diagnostic tool. Some research suggests sex hormones modulate immune responses: estrogens may promote a Th2-dominant profile, potentially increasing allergic susceptibility, while progesterone and testosterone can be immunosuppressive. Cortisol influences inflammation but chronic elevation impairs immune regulation. However, these effects are small and inconsistent. In clinical practice, hormone testing is not used to diagnose or manage allergies. It may provide context in complex cases with suspected hormonal-immune interaction, but it is not a substitute for standard allergy diagnostics (specific IgE, skin prick tests). Evidence is weak, based on observational and mechanistic studies.